Wednesday, May 6, 2020

Formal and Informal free essay sample

Robin Phillips Assignment: The Learning Autobiography Formal and Informal Learning Date: August 26, 2010 I started my formal education in elementary school when I traveled with my parents. My father was in the United States Army, and I lived in Germany for three years. Then we moved to Japan where I lived for four years. The two things that stuck in my mind were the earthquakes we had every day and my dogs being very scared. I began junior high school in Colorado Springs, Colorado where I took the classes that were required. I had a hard time with math and reading. I learned that I had dyslexia and had to be in special education classes. I had to learn by hands on and showing me how to do things over and over. This had to be done many times until I understood it . While in junior high the one thing stuck out for me, I was good in my choir class and every one liked hearing me sing. We will write a custom essay sample on Formal and Informal or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page I could sing harmony while others sang in the background for me. High school was harder for me, as the classes became more difficult and I had to work really hard to get good grades, in order to pass them. There was one teacher who helped me with my speech class and she would take time to listen to my speeches that I prepared. She always wanted to make sure I had the speeches timed down to the minute. Her name was Ms. Muto. Ms. Muto also helped me with my computer work, to make sure I understood how to write the programs on the homework that was given to me back in 1983. I went on to graduate form Apache Junction High School in 1985 and received my diploma from there. When high school was done I did different kinds of jobs but I never found anything that I was good at. I worked in two different nursing homes, but I was too small of a person to lift people, so I quit. Also, I was not trained on how to handle elderly people. I mostly helped the LPN’s in what ever they needed done. My brother was a nurse and told me some of the things that I needed to know, but I never could understand what he told me. I started at Mesa Communityback in 1991. I started with lower grade classes first because I scored low when I took the placement tests that every student has to take before getting any of their classes. I worked my way up to the higher level of classes. here where many people who helped me on my learning journey at MCC. There was one person that always helped me get the classes I needed. Her name was Judy and she was a disability specialist. She always took special time with me and I will never forget her. Judy passed away in 2008 of breast cancer. I didn’t go every semester at MCC due to a illness that required me to have a hysterectomy a t the age of 28. When I was well enough I started back at MCC. I took English 101 when I started back and I loved it because the instuctor who did the class gave everybody special time on all work. I did take a communications class over because I failed it the first time. My instuctor Mr. Mancuso sat down with me and said â€Å" you can do all the papers over and you will pass. I thanked him for being so kind to me. In May 2007 I graduated from MCC. I am the only one in my family that has a 2 year degee. In conclusion, I have had many challenges in my life and stuggles with education due to the disability that I have had to contend with all my life. I will work very hard to get this next degree at Ottawa because I want to help people with their problems, when I get this degee.

Tuesday, May 5, 2020

Cell Structure and Functions

Question: Describe about the Cell structure and function? Answer: Definition: Lysosomes are tiny vesicles filled with hydrolytic enzymes (proteins which are catalyst for thousands of metabolic reactions that are required for life) which are required by cells to metabolize its nutrients and for removing dead cells from body by destroying them. They are the main site for digestion or breakdown of structures inside the cells [1]. Proteasome on the other hand works by the process of proteolysis (chemical reaction which cleaved peptide bonds) where its main function is to destroy damaged or unwanted proteins. Enzymes involved in process of proteolysis are known as proteases. Cells require proteasomes majorly to regulate and maintain concentration of properly folded proteins and remove those that are in excess or are misfolded [2]. Location: Lysosomes are membrane bound cell organelle found mostly in all animal cells except red blood cells but are rarely found in plant cells, whereas proteasomes are present in all eukaryotes (inside nucleus and in cytoplasm), archaea and in some bacteria as well [3, 4]. Comparison of Functions of lysosomes and proteasomes When food particle is taken up or absorbed by cells, lysosomes release enzymes in order to break those molecules (sugar or protein) into usable form of energy for cells to survive. Lysosomes carry the process of digestion/breakdown of macromolecules like carbohydrates, nucleic acids, proteins and lipids as they have acidic pH [3], whereas proteasomes only remove misfolded/abnormal proteins formed in cells [4]. Secondly lysosomes repair the membrane of cells, on the other hand, proteasome are responsible for differentiation of cells (work by degrading metabolic enzymes and transcription factors) and also for cell cycle regulation and cellular differentiation. Preotasomes are also helpful for cells to respond to stress, where the ubiquitin conjugated regulatory proteins are degraded. Whenever any pathogen enters human body, macrophages engulfs the pathogen and the vesicle containing pathogen is pinched off the macrophage, further this vesicle fuses with the lysosomal membrane and lysos omes respond to foreign pathogens like viruses, bacteria and some antigens which enter in cells, by digesting them using digestive/hydrolytic enzymes but proteasomes play essential role in immune system as they generate antigenic peptides which are further presented by the major histocompatibility complex I (MHC I) molecules to T cells and these T cells then clear off the pathogen and activate B cell to develop memory against those pathogens and thus the antigens are then cleared from the body [3,4]. Comparison of protein components of Lysosomes and Proteasomes Lysosomes are made up of proteins which are basically enzymes present on the lysosomal membrane consisting of lipids. Integral membrane proteins which are specific to lysosomes are called as Lysosome Associated Membrane glycoproteins (LAMPs) for which no such clear function is found. Considering their structure, these proteins have two internal lysosome-luminal domains that are homologous and are separated by hinge region that is rich in proline content. The proteins have transmembrane region at their C-terminal extremity which is followed by a short cytoplasmic tail [5]. As compared to lysosomes which have enzyme (protein) and an outer membrane, proteasomes subcomponents are denoted by their Svedberg sedimentation coefficient (S). In mammals, most exclusively used proteasome is 26S proteasome (~2000 kDa) which has single 20S subunit and two 19S subunits, acting as regulatory caps. The core of this proteasome is hollow which acts as an enclosed cavity where proteins are degraded. 19S subunits at each end of the core particle has many Ubiquitin binding and ATPase active sites. This portion identifies polyubiquitinylated proteins and sends them to catalytic core. An 11S particle can link with core particle in a similar way as of 19S and contribute in clearance of any foreign peptides. Image courtesy :- McNaught, K. S. P., Olanow, C. W., Halliwell, B., Isacson, O., Jenner, P. (2001). Failure of the ubiquitinproteasome system in Parkinson's disease.Nature Reviews Neuroscience,2(8), 589-594. In eukaryotes, 19S has 19 different proteins which are divided in two sub-assemblies, a 10-subunit lid and a 9-subunit base (of which 6 are ATPase subunits) which directly binds to 20S core particle at the -ring. This attachment of 19S and 20S units needs binding of ATP to ATPase subunit of 19S. In order to degrade ubiquitinylated and folded proteins using assembled complex, ATP hydrolysis is required in only one step and rest steps can work by just presence of bound ATP [6]. Thus we can conclude by saying that lysosomes are, protein (enzyme) containing vesicles which degrade pathogens or food particle to get rid of infection or release energy respectively and proteasomes on the other hand are responsible for removing improperly folded or ubiquitinylated proteins formed in our body failing which the bodys regular functions may be altered in a negative manner. References: 1. Aronson, N. N., de Duve, C. (1968). Digestive activity of lysosomes II. The digestion of macromolecular carbohydrates by extracts of rat liver lysosomes. Journal of Biological Chemistry, 243(17), 4564-4573. 2. Ding, W. X., Yin, X. M. (2008). Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome. Autophagy, 4(2), 141-150. 3.https://www.boundless.com/biology/textbooks/boundless-biology-textbook/cell-structure-4/the-endomembrane-system-and-proteins-61/lysosomes-321-11457/ 4. Peters, J. M., Franke, W. W., Kleinschmidt, J. A. (1994). Distinct 19 S and 20 S subcomplexes of the 26 S proteasome and their distribution in the nucleus and the cytoplasm. Journal of Biological Chemistry, 269(10), 7709-7718. 5. https://www.ebi.ac.uk/interpro/entry/IPR002000 6. Wang, J., Maldonado, M. A. (2006). The ubiquitin-proteasome system and its role in inflammatory and autoimmune diseases. Cell Mol Immunol, 3(4), 255-261.

Saturday, April 11, 2020

A Final Narrative Essay Sample

A Final Narrative Essay SampleI have often thought that if the writers were given an essay sample they would be forced to really focus on the quality of writing. If they didn't, they could simply submit their story that was just found in the middle of the file folder and no one would care. But I guess they do, because the story would simply not interest anyone.It doesn't matter if the story is good or not. If it is not the writer can always try again in a few months. But the fact is that every writer has probably written several stories. If you are at this point, you should consider taking a paragraph sample form an article site, because if you can get a paragraph as long as the essay, then that would make a great essay.For those who want to publish an essay in a publishing house, I think you should get this sample anyway. So why not submit it?You will find that most sites that offer this sort of sample offer a collection of stories. And I assume that the stories in this collection w ill be published someday, so I suppose that there is no harm in submitting them. So I would send along a few samples.The first one you might consider is the first one. The writer may have heard about the story first in print. But it does not have to be in print. You could send it to your friends if you know of any who will like it.You should send out your story to have it reviewed by another person. If the reviewer feels that the story is good and the writer can pass the review, then they will probably publish it, if it was good, they would publish it for free.With a paragraphsample you will find that you do not have to worry about the rest of the essay. You will get your writer's block over before you know it.

Sunday, March 8, 2020

Free Essays on A Biblical Theology Of The Pastoral Role

In Search of the Shepherd: A Biblical Theology of the Pastoral Role As a college student, I find that the one question asked of me most frequently is, â€Å"What is your major?† At first I thought it was quite normal to respond that I was pursuing a pastoral major at Moody Bible Institute. But after going through this routine a hundred times, I have come to the conclusion that no one has any idea what I am talking about when I use the word â€Å"pastor†. The responses are extremely varied. â€Å"You mean you’re gonna be a priest?† or, â€Å"There’s a school for that sort of thing?† or, â€Å"You’re already a pastor, we’re all pastors in the Lord† and even, â€Å"Your father must have been a minister, right?† Clearly, this world has become very confused about the role and nature of the pastor. The previous conversations were mostly with unbelievers, and I think we can cut them some slack on their ignorance of the church. It would be my hope that when we turn our attention to the church, we would find a better understanding of who the pastor is to be. But as many know, this is far from the truth. It seems that every church I walk into has a radically different definition of the word pastor. At first I was tempted to shrug this off as a matter of personality differences. But I find that many church leaders are following the examples of other prominent Bible teachers, going out of their way to â€Å"overcome† their own personalities in order to emulate what they view as a â€Å"good pastor†. Any book about pastoral ministry today will report the current trend toward pragmatism in ministry: If it seems to work, then it must be the right way to do things. Every Christian today has opportunities to view and experience ministry from the most thriving churches in the country through radio, television, videos, and magazines. Great pressure comes upon our church leaders through this. People from their congregations learn abou... Free Essays on A Biblical Theology Of The Pastoral Role Free Essays on A Biblical Theology Of The Pastoral Role In Search of the Shepherd: A Biblical Theology of the Pastoral Role As a college student, I find that the one question asked of me most frequently is, â€Å"What is your major?† At first I thought it was quite normal to respond that I was pursuing a pastoral major at Moody Bible Institute. But after going through this routine a hundred times, I have come to the conclusion that no one has any idea what I am talking about when I use the word â€Å"pastor†. The responses are extremely varied. â€Å"You mean you’re gonna be a priest?† or, â€Å"There’s a school for that sort of thing?† or, â€Å"You’re already a pastor, we’re all pastors in the Lord† and even, â€Å"Your father must have been a minister, right?† Clearly, this world has become very confused about the role and nature of the pastor. The previous conversations were mostly with unbelievers, and I think we can cut them some slack on their ignorance of the church. It would be my hope that when we turn our attention to the church, we would find a better understanding of who the pastor is to be. But as many know, this is far from the truth. It seems that every church I walk into has a radically different definition of the word pastor. At first I was tempted to shrug this off as a matter of personality differences. But I find that many church leaders are following the examples of other prominent Bible teachers, going out of their way to â€Å"overcome† their own personalities in order to emulate what they view as a â€Å"good pastor†. Any book about pastoral ministry today will report the current trend toward pragmatism in ministry: If it seems to work, then it must be the right way to do things. Every Christian today has opportunities to view and experience ministry from the most thriving churches in the country through radio, television, videos, and magazines. Great pressure comes upon our church leaders through this. People from their congregations learn abou...

Friday, February 21, 2020

Assignment Example | Topics and Well Written Essays - 250 words - 102

Assignment Example The Royal British Museum obviously hopes to attract the tourist interested in history and in learning about Canada’s cultural background. Niagara Falls would be more appropriate for families with children as well as adults who want to enjoy a beautiful view. The Museum of Anthropology is a more specialized experience and is an aboriginal experience. As one of Canada’s most significant buildings The Museum of Anthropology’s (About†¦) archaeological beauty and world class collections are showcased, the Museum is Canada’s largest teaching museum. Niagara Falls is a natural attraction that has been visited for more than a hundred years though it has in recent years become a huge attraction for commercial tourism which is a contrast to niche marketing. Mass marketing aims to reach all spectrums of tourist. Niche tourism could be divided into further specialized areas such as rural-Field Stone Vineyards in Alberta, a local Canadian restaurant as part of a gastronomy experience or a sports theme tourist attraction. Obviously these niche markets can be further specialized according to type of wine produced, type of restaurant food, and specific sport. Small scale operations more closely fit with the tailored specifics of niche tourism and the definition has taken on a more common sense meaning, related directly to how specific of a target attractions or any other product are aiming for. Novelli, M. (2005). Amazon.com: Niche Tourism: Contemporary issues, trends and cases (9780750661331): Marina Novelli: Books. Amazon.com: Online Shopping for Electronics, Apparel, Computers, Books, DVDs & More. Retrieved February 6, 2012, from

Wednesday, February 5, 2020

Assess the moral arguments and political actions of those who opposed Essay

Assess the moral arguments and political actions of those who opposed to the spread of slavery in the context of the mexican war and the Kansas-Nebraska act - Essay Example The Kansas-Nebraska act also pushed the country into civil war and divided the nation into two factions. The act also gave rise to a new Republican Party arguing abolishment of slavery. The arguments of Republicans against slavery were based on morality. Republicans treated everyone equally and considered freedom the most basic right. Lincoln said in his famous Lincoln-Douglas Debate â€Å"I agree with Judge Douglas he is not my equal in many respects—certainly not in color, perhaps not in moral or intellectual endowment. But in the right to eat the bread, without the leave of anybody else, which his own hand earns, he is my equal and the equal of Judge Douglas, and the equal of every living man† (Lincoln). It is important to note that those who opposed slavery were not in favor of total social equality between people of all races. However they believed that blacks were also humans and they should be treated with respect. Lincoln was actually afraid that popular sentiment would be in favor of slavery and then it would be impossible to demolish the institution of slavery from America for ever. The moral arguments of Republicans were not ideal but still they provided room for some sort of acceptance of blacks. They were saying that blacks were not equal but this does not mean that their freedom should be taken away. Social equality was not argued but practicality and humanity was made basis for abolishment of slavery. The famous poet James Russell Lowell called those people slaves who did not dare to speak for the weak (344). He was a poet who was strongly against slavery and his poems reflected his passion towards abolishment of slavery. He considered slavery immoral and devoted his poetry against it. Wilmot Proviso can be seen as an attempt to curb the spread of slavery and mitigate differences between pro and anti slavery politicians. It was presented by a Democrat David Wilmot and the